Virginia Research Day 2021

Medical Resident Research Case Reports

24 Infective Endocarditis in a 73-year old Female: A Case Report

Tiffany Bryan, DO; William Cox, DO Corresponding author: Tiffany.bryan@hcahealthcare.com

LewisGale Hospital-Montgomery

References

Native valve infective endocarditis is uncommon, with an incidence of approximately 2 to 10 cases per 100,000 person-years (1). Infective endocarditis occurs when collagen and other molecules becomes exposed and form a thrombotic lesion. This lesion is susceptible to the colonization of bacteria, leading to further platelet and fibrin deposition to form an infected vegetation (1). There are numerous risk factors for the development of Infective endocarditis, including neoplastic disease. Overall, gram positive bacteria account for 80% of all cases of Infective endocarditis (1.) Staphylococcus aureus occurs in 35 to 45% of these cases (1,3). Staph aureus typically causes acute endocarditis with damage to cardiac valves, embolization of vegetation’s to extra cardiac sites and can progress quickly to death if untreated (2). We present a case of a 73-year old Female who

had untreated squamous cell cancer for twenty years, leading to mitral valve failure secondary to Infective endocarditis. This research was supported (in whole or in part) by HCA Healthcare and/or an HCA Healthcare affiliated entity. The views expressed in this publication represent those of the author(s) and do not necessarily represent the official views of HCA Healthcare or any of its affiliated entities.

Chambers, H, et al. Native Valve Infective Endocarditis. The New England Journal of Medicine. 2020, 383,6. Mohiyiddeen, G, et al. Infective endocarditis caused by Staphylococcus aureus in a patient with atopic dermatitis: a case report. Journal of Medical Case Reports. 2008, 2, 143. Cahill, T, et al. Infective endocarditis. The Lancet. 2016, 387, 10021.

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