Virginia Research Day 2021

Medical Resident Research Case Reports

06 A Case Report of Satisfactory Post Left Knee Replacement Pain Control after Switching from Oxycodone to Buprenorphine

Shuo Qiu MD 1 ; Sachinder Vasudeva MD 2 Corresponding author: sqiu@carilionclinic.org

1 Carilion Clinic-Roanoke 2 Salem VA Medical Center-Salem

This case report demonstrates using buprenorphine 32 mg to achieve adequate pain control after a total knee replacement. The patient stopped buprenorphine 48 hours before surgery. He was prescribed 150 tablets of oxycodone 5mg. After finishing oxycodone, he experienced significant pain that was relieved by 32 mg of buprenorphine daily. Urine drug screens (UDS) were negative perioperatively. To our knowledge, this is the first case of successful acute postoperative pain management using buprenorphine. Buprenorphine offers many unique advantages in acute pain control, including lower risk of respiratory depression, abuse potential, and lower risk of nephrotoxicity.

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