Via Research Recognition Day Program VCOM-Carolinas 2025

Case Reports

Tracheobronchial Amyloidosis Causing Left Lung Collapse: A Case Report Rayhan Karimi, OMS-IV, Arun Adlakha, M.D. VCOM Carolinas, Spartanburg, SC. Purpose: To increase medical knowledge, treatment, and patient presentation of tracheobronchial amyloidosis

I n t rAobdsut cr at icotn

Imaging and Bronchoscopy

Bronchoscopy cont.

‹‰—”‡ ͷǤ ƒ‰‡• ‘ˆ –Š‡ Ž‡ˆ– ƒ‹ •–‡ „”‘ Š—• ƒ† ‹‘” ƒ ”‘‹•ƒ– ”•‹Š ‘– ‹™˜ ‡‹ Ȁ ‰ ‘ Ž—•‹˜‡ †‹•‡ƒ•‡ ƒ† — ‘•ƒŽ ‘†—Žƒ” †‹•‡ƒ•‡ ’”‘Œ‡ –‹‰ ‹–‘ –Š‡ Ž—‡Ǥ

Case Presentation • ” ‘  ” ›Š‘‘–•Š ‡‘”’ƒ‹’ ›‹ǡ ƒ–‡ ”†˜ ‡ ‡– ‹ Š‘ ƒ • ǡ‹ •ƒ—Ž †Š‡ ƒ„•— ŽŽƒ•‹‡”‰ ǡ– Šƒ ‡” ‡” ƒ ’ ›ǡ ‘‘Ž› ‡’Ž‘›‡† –‘ ”‡‘˜‡ ‘„•–”— –‹˜‡ ƒ›Ž‘‹† †‡’‘•‹–• ƒ† ‹’”‘˜‡ ƒ‹”™ƒ› ’ƒ–‡ › ͸ͳǦ›‡ƒ”Ǧ‘Ž† ƒŽ‡ ™Š‘ ‘’Žƒ‹‡† ‘ˆ — ‘‹† ’”‘†— –‹˜‡ ‘—‰Šǡ †›•’‡ƒǡ ™Š‡‡œ‹‰ǡ ƒ† Š‡•– –‹‰Š–‡•• ˆ‘” –Š‡ Žƒ•– •‡˜‡”ƒŽ ›‡ƒ”•Ǥ Š›•‹ ƒŽ ‡šƒ‹ƒ–‹‘ ”‡˜‡ƒŽ‡† ƒ—†‹„Ž‡ ™Š‡‡œ‹‰ ƒ† ‡’‹•‘†‡• ‘ˆ ’”‘†— –‹˜‡ ‘—‰Š ™‹–Š ’—”—Ž‡– •’—–—Ǥ ‘ Š‡‘’–›•‹• ™ƒ• ‘–‡†Ǥ ‡ ™ƒ• ƒˆ‡„”‹Ž‡ ™‹–Š ” • ” ‡ – ‘ ƒ • ‘ ’ „  ‹ Ž ” ‡ ƒ ƒ ˜ – ‹ ‘ ‹ ” – ” ƒ ‘ › Ž š • ” › ‹ ƒ ‰ ‰ – ‡  ‡  • ™ ǡ • ‡ ƒ ƒ š • – — ʹ ‡ ” ͷ ’ ƒ – – „ ‹ ˆ ” ‘ ‘ ‡  ” ƒ  ‘ –Š ˆ ‹ • ͻ Ž † ’ ͸ – ‡ Ψ ƒ ”… Ǥ  Š › Š ‹ ’ ‡ —  • – – ‡ ‡ ƒ ‡ ™ Ǥ š ƒ ‹  – ‹ Š • ‹ ”  ” ‡ ‡ ƒ • • – – – ‹ ‹ ‘ ‹    ‰ ‰ ”‡˜‡ƒŽ‡† • ƒ––‡”‡† „‹Žƒ–‡”ƒŽ ”Š‘ Š‹ ƒ† ”ƒ Ž‡• ‘˜‡”Ž›‹‰ –Š‡ ”‹‰Š– ‹†Ǧ Š‡•– ƒ† „ƒ Ǥ ‹• Žƒ„ –‡•–• ”‡˜‡ƒŽ‡† ‹Ž† Ž‡—‘ ›–‘•‹• ™‹–Š †‘‹ƒ– ‡—–”‘’Š‹Ž‹ƒǤ ƒ•‡Ž‹‡ •’—–— ƒ† „Ž‘‘† —Ž–—”‡• ™‡”‡ •‡– ™Š‹ Š ™‡”‡ ‡‰ƒ–‹˜‡Ǥ • ”ƒ Š‡‘„”‘ Š‹ƒŽ ƒ›Ž‘‹†‘•‹• ‹• ƒ ”ƒ”‡ †‹•‘”†‡” Š ƒ’””ƒ‘ ––‡‡‹ ”‹•œ ‡™†‹ –„Š›‹ – Š – ‡Š ‡ƒ „– ”ƒ‘ ”Š‡ ƒƒ Žƒ †‡†’ „‘”•‘‹ –‹ ‘Š‹ ƒ‘ Žˆ ™ƒ ƒ Ž›Ž •Ž ‘ǡ ‹ † Ž‘‡„ƒ •†–‹”—‰ –– ‘‹ ‘ ”‡ǡ • ’Š‹””‘ƒ – ‘‹ ” › ‘ —‘ ‰ Š’ǡ Ž†‹ ›ƒ•–’‹ ‘ ‡ ƒ• ǡ • ƒ— †Š ”ƒ‡• ƒ—‹”””™‡ ƒ ›– ‹ˆ‡ –‹‘•Ǥ • ‹•–‘Ž‘‰‹ ƒŽŽ›ǡ –”ƒ Š‡‘„”‘ Š‹ƒŽ ƒ›Ž‘‹†‘•‹• ‹• ‹†‡–‹ˆ‹‡† „› –Š‡ ’”‡•‡ ‡ ‘ˆ ƒ‘”’Š‘—• ‡‘•‹‘’Š‹Ž‹ †‡’‘•‹–• ™‹–Š‹ –Š‡ •—„— ‘•ƒ ‘ˆ –Š‡ –”ƒ Š‡‘„”‘ Š‹ƒŽ –”‡‡Ǥ

˜‹ ‹‰‡—™” ‡ ‘ ͳˆ Ǥ Š š‡ ‹•ƒ– Ž •Š‘™‹‰ ‹””‡‰—Žƒ” ƒ–ŠŽ ‹‹ ˆ‹ ‡ƒ–‹‹‘‰ ™‘ ˆ‹ ––ŠŠ ‡ –”ƒ Š‡‘„”‘ Š‹ƒŽ ƒ‹”™ƒ›• ȋƒ””‘™•ȌǤ

‹‰—”‡ ʹǤ ‘‰‘ ”•‡Š†‘ ™• – ‹ƒ‹ ‰ ‡– †Š ‡• Ž”‹‡††‡ Š‹‰ŠŽ‹‰Š–‡† ƒ  ›„Ž ‘‡ ‹†‡ †ƒ –‡Š’ ‘– Š• ‡‹ – ‹ ‘  — ‘•ƒŽ •—”ˆƒ ‡

‹‰—”‡ ͸Ǥ ”‘ Š‘• ‘’‡ ‹ƒ‰‡ •Š‘™‹‰ ƒ Ž—•–‡” ‘ˆ ‘†—Žƒ” — ‘•ƒŽ Ž‹ ‡ •– ‹‘‘ –Š•‡ ’ Ž ”—‘Œ ‡‡ – ‹ǡ ƒ ‰– –Š‡ Ž‡˜‡Ž ‘ˆ –Š‡ ’”‘š‹ƒŽ –”ƒ Š‡ƒǤ

‹‰—”‡ ͵Ǥ ‘”‘ƒŽ ˜‹‡™ ‘ˆ Š‡•– •Š‘™‹‰ „‹Žƒ–‡”ƒŽ ‹””‡‰—Žƒ” –Š‹ ‡‡† ƒ† ƒ ” ”ƒ‘Ž ™‹ ˆ•‹Ȍ‡ †™ ‹ƒ–‹Š” ™Š ‹ƒ‰›Š• Ǧ ȋ‰””‡ƒ†† ‡ „”‘ Š‹ƒŽ ƒ””‘™‹‰ ƒ† ‘ Ž—•‹‘ ‘ˆ Ž‡ˆ– „”‘ Š‹ƒŽ –”‡‡ ȋ‰”‡‡ ƒ””‘™ȌǤ

Diagnosis and Conclusions

Acknowledgements and References ˆ ‹ —†‡‹  –‰‘• – ‘Š ˆ‡ ’„ ‘” ‘• ‹ – ‹ ˜Š‡‘ • ‘‘’‰‹‘ ƒ ‡ †† Š• –‹ ƒ• –‹ ‘ Ž‹ ‘ ‰‰ ‹ǡ –ƒŠŽ‡ ’ƒ–‹‡– ™ƒ• †‹ƒ‰‘•‡† ™‹–Š Tracheobronchial Amyloidosis • ‘–‹—‘—• ‘‹–‘”‹‰ ‹• ”— ‹ƒŽ –‘ ƒ••‡•• ˆ‘” ’”‘‰”‡••‹‘ –‘ — ‘•ƒŽ ‘†—Žƒ” ƒ† ‹ ‘ • ‡•˜– ”‡‹” ‡– ‹”˜‡‡•ǡ ’‘‹ ” ƒŽ–—‘•”‹›˜ ‡ ‘†‹ • ‡’ƒŽ ‹• ‡ƒǡ– ™‹ ‘Š‹• Šƒ  †ƒ ” ‡ ”“‡—• —‹ ”Ž‡– ‘”‡ ƒ‰‰”‡••‹˜‡ ‹–‡”˜‡–‹‘•Ǥ • – ”—‡”ƒ – ƒ •‡‡ •– — – ’‘ ’ ƒ‘˜”‘–‹•† ‘ ˆŠˆ ‡ƒ”‹ ‡‰• ’ ‘ƒˆ– ‹Ž ‡‹ ˆ‡ –Ǧ •– Š ƒ”‰‡‰ƒ”–‡‡••‹ ‹˜‰‡ ‘’Ž‹ ƒ–‹‘• ƒ† ˆ‘” •›’–‘ƒ–‹ ”‡Ž‹‡ˆǤ

‹‰—”‡ ͶǤ ”‘ Š‘• ‘’‡ ‹ƒ‰‡ •Š‘™‹‰ ƒ –Š‹  –—Š ‡— •Ž ‡ ’ˆ –Ž —‰ƒ ‘‹  •Ž —– ‡†‹  ‰ „”‘ Š—• ȋ”‡† ƒ””‘™ȌǤ

2025 Research Recognition Day

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