Virginia Research Day 2022

Medical Student Research Cl inical

Mahnoor Khurshid, OMS II; Maha Nayyar, MPH, MS, OMS II; Julie Mehta, MA, OMS III; Sofia Abraham-Hardee, DO, PhD, FACOP, FAAP, CS; Theresa J McCann, MPH, PhD Corresponding author: Mkhurshid@vcom.edu 14 A Review Of Human Papilloma Virus (HPV) Vaccination Uptake In New Beginnings Pediatrics Clinic, Blacksburg, VA

VCOM Virginia New Beginnings Pediatrics Clinic, Blacksburg, VA

Introduction: Human papilloma virus (HPV) is the most common sexually transmitted infection in the United States, and a preventable cause of cervical cancer.1 Vaccine uptake tends to be low, with an earlier estimates of <50% of adolescent girls and 20% of adolescent boys having received the full course of HPV vaccine.2 Objective: Examine HPV vaccine uptake, completion, and adherence to the CDC vaccine schedule at the New Beginnings Pediatric Clinic in Blacksburg, Virginia to further our understanding about trends of vaccination uptake in this region. Methods: A retrospective chart review of patient records at the New Beginnings Pediatrics Clinic in Blacksburg, Virginia was conducted to obtain de-identified medical records of patients who have either initiated and/or completed the HPV vaccination series between January 1, 2012, and December 30, 2020. Information was obtained on age, race/ ethnicity, gender, date/age of each vaccination dose, HPV series completion, and vaccine adherence. Records were obtained for 516 patients seen at the Clinic during this period.

Results: Amongst the cohort of patients from New Beginnings Pediatrics Clinic who received the HPV vaccine, our data showed that vaccination uptake was higher in female patients compared to male patients. Additionally, our results demonstrated that the average age for the first dose of the vaccine was initiated at around 13.6 years, which falls within the recommended age of 9 to 14 years as per the CDC guidelines. However, we observed that the average starting age was on the higher end of that recommended age group. Also, while 60% of the patients did in fact complete the recommended vaccine series, there were about 40% of patients who did not. There was no difference in vaccine completion by gender (P=0.36). Of the patients that did complete either the two or three dose series, 66% adhered to the CDC recommended schedule. Lastly, there was a significant difference when comparing females vs males for completing the series and adhering to the CDC recommended schedule (P=0.01). Conclusion: While there is no difference in completion of the dose series among gender, there is a difference in CDC vaccine adherence, with girls having increased adherence to the

CDC schedule. Additionally, 60% of patients that received a dose, completed the dose series, which is higher than the national average of only 51% adolescents completing the dose series.3 Further research will investigate demographic characteristics of all patients between the ages of 9 to 21 years at New Beginnings Pediatrics Clinic in order to compare those new data to our gathered data of patients who received the HPV vaccine. References: https://www.cdc.gov/hpv/hcp/index.html National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, National Center for Immunization and Respiratory Diseases, National Center for Chronic Disease Prevention and Health Promotion Eliscu, A. Human Papillomavirus and HPV Vaccines. American Academy of Pediatrics, Peds in Review, 2017;38:443. https://www.cdc.gov/hpv/partners/outreach- hcp/hpv-coverage.html

78