VCOM Louisiana Research Day Program Book 2024

Education, Simulation and Best Practices

Paxton Holder, OMS-III; Savannah Newell, PhD VCOM-Louisiana 60 RELIABILITY OF CADAVERIC ARTERIAL HISTOLOGY

scoring system. A ꭓ -square test will be used to compare tissue groups with different amounts of environmental exposure. Tissue quality and reliability will be reported for the overall sample group as well as for subgroups based on approximate environmental exposure time between dissection and specimen collection. Results: This study is still in progress, but we expect to show that embalmed cadaver arterial tissue is a reliable source for analysis of tissue and human pathology in medical education and research. This will expand the current literature that examines various other cadaver tissues, and this will be important for medical education. The possibility of using cadavers to accurately study human pathology on the microscopic level will allow students to gain a greater understanding of the associated pathophysiology and clinical manifestations. Conclusions: Cadavers are a wonderful resource for medical education on the macroscopic level. In this study, we hope to expand the utility of this resource to the microscopic level by showing that cadaver tissue produces reliable histology.

Background: Scholarly activity is an integral component of medical education and practice, and cadavers are an excellent population of readily accessible subjects. Cadaveric tissue has been used to study human pathology and tissue analysis, but the quality and reliability of histological sections produced from this tissue is a point of investigation. Objective: The aim of this study is to specifically assess the histological quality and reliability of cadaveric vascular tissue specimens. Methods: The cadavers in this study are from the VCOM-Louisiana campus in Monroe, Louisiana. Students dissect cadavers in a systems-based approach to match the didactic curriculum. Approximately 5 centimeter sections of select arterial groups were collected. Due to the systems-based approach of the dissection, arterial samples were collected with differing amounts of environmental exposure. All samples were stored in formalin 10% solution until tissue processing began. The tissues were processed, embedded in paraffin, sectioned at 5 micrometers, and stained with H&E. For the purposes of this study, tissues will be evaluated by a board certified pathologist to assess the quality of preservation using an adopted

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