VCOM 2023 Annual Report

VCOM Funded Seed Grants (continued)

Kristina Zarenko PhD • REAP: Assessing the Effectiveness of Cadaver Wrist Fracture Integration in Ultrasound Training. Dr. Zarenko serves as Co-PI with Colleen Cheverko, PhD and Jacob Turnbull, DO. Colleen Cheverko, PhD • REAP: Assessing the Effectiveness of Cadaver Wrist Fracture Integration in Ultrasound Training. Dr. Cheverko serves as Co-PI with Kristina Zarenko, PhD and Jacob Turnbull, DO. Jacob Turnbull, DO • REAP: Assessing the Effectiveness of Cadaver Wrist Fracture Integration in Ultrasound Training. Dr. Turnbull serves as Co-PI with Kristina Zarenko, PhD and Colleen Cheverko, PhD.

• Delta-CRP: Oleocanthal as a novel SMYD2 modulator for the control of prostate cancer. Dr. Elmageed serves as PI on this project along with a collaborator from the University Louisiana Monroe College of Pharmacy. Stephen DiGuiseppe, PhD • Delta-CRP: Development of a three dimensional human skin equivalent cell culture model to investigate poxvirus infection. Stephen DiGuiseppe, PhD serves as PI on this project along with a collaborator Lin Kang, PhD • Delta-CRP: Identifying molecular mechanisms that upregulate expression of mutant proteins to generate cancer stem cells. Lin Kang, PhD serves as PI on this project along with a collaborator from the University Louisiana Monroe College of Pharmacy. Pawel Michalak, PhD • VCOM & VMCVM One Health Program: An integrated experimental, computational, and field-based strategy to study viral emergence risk. Dr. Michalak is Co PI on this project with a collaborator from VMCVM. Sarah Voth, PhD • REAP: Cytoprotective Lung Endothelial Amyloids. Dr. Voth serves as Co-PI with Adam Morrow, PhD and Rebekah Morrow, PhD on this project. from the University Louisiana Monroe College of Pharmacy.

with a collaborator from VMCVM.

Albert Kozar, DO • REAP: The Effects of Light on Platelet Activity. Jessica Gilbertie, DVM, PhD serves as Co-PI. Alison LePera, DO, PhD • REAP: Evaluating the Effectiveness of Using a Low-Cost, High Fidelity Model to Train Procedural Competency in Ultrasound Guided Pericardiocentesis Jonathan Millard, PhD • REAP: Development of a Novel 3D Geometric Morphometric Landmarking Technique for Application in Chiari Malformation Kelly Roballo, DVM, PhD • VCOM ICTAS (matching funds from VT ICTAS) Investigating the regenerative potential of stem cells for use in blast spinal cord injury. Dr. Roballo serves as Co-PI on this project with a faculty member from Biomedical Engineering and Mechanics. Chris Reilly, PhD • VCOM & VMCVM One Health Program: Gut microbiota dependent regulation of SLE pathogenesis. A collaborator from VMCVM serves as Co-PI with Dr. Reilly on this project. Dean Sutphin, PhD • REAP: Toward a NextGen Surveillance System for Infectious Disease (NGSSID) across VCOM’s Central America and Caribbean Regional Network. Dr. Sutphin serves as Co-PI with Pawel Michalak, PhD, and Stephen DiGuiseppe, PhD. David Redden, PhD, Lin Kang, PhD, and Kasia Michalak, MSc serve as Coinvestigators. Note since P. Michalak and S. Digiuseppe are Co-PIs also, this should be listed under their names as well (both at LC).

Virginia Campus

Ramu Anandakrishnan, PhD • REAP: Confirming immunosuppressive clonal

hematopoietic (CH) mutations in tumor infiltrating immunocytes (TII) in lung adenocarcinoma (LUAD). Mark Joseph, MD, Carilion Clinic serves a Co-PI, along with co investigator sKrit Ritthipichai, PhD; Zak Elmageed, PhD and Robin Varghese, PhD.

Blaise Costa, MPharm, PhD • VCOM ICTAS (matching funds

from VT ICTAS) To Study Traumatic Brain Injury Induced Oscillation of Glutamate Pendulum & Chemical Clamps to Hold Dr. Costa serves as Co-PI on this project with a faculty member from Biomedical Engineering and Mechanics.

Adam Morrow, PhD • REAP: Cytoprotective Lung

Endothelial Amyloids. Dr. Morrow serves as Co-PI with Sarah Voth, PhD and Rebekah Morrow, PhD on this project.

Jessica Gilbertie, DVM, PhD • VCOM & VMCVM One Health

Rebekah Morrow, PhD • REAP: Cytoprotective Lung

Program: Development of a canine model of recurrent uropathogenic E. coli infection for evaluation of a novel biologic therapeutic. Dr. Gilbertie is Co-PI on this project

Endothelial Amyloids. Dr. Morrow serves as Co-PI with Sarah Voth, PhD and Adam Morrow, PhD on this project.

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