VCOM 2021 Annual Report

RESEARCH

Virginia Campus

treatment. Dr. Hrubec is Co-PI on this project with a collaborator from VMCVM. Two investigators from VMCVM are also involved in this project.

A collaborator from VMCVM serves as Co-PI with Dr. Reilly on this project. Beverly Rzigalinski, PhD • VCOM REAP: Improving blood storage with cerium oxide nanoparticles. A faculty member from Harvard University is an investigator on this project. • VCOM REAP: The effects of light on platelet activity. Al Kozar, DO, serves as Co-PI on this study. Dean Sutphin, PhD • VCOM REAP: Third-generation DNA sequencing approaches to rapid characterization of drinking water contamination in El Salvador, Honduras, and the Dominican Republic. Dr. Sutphin’s Co-PI is Pawel Michalak, PhD. Lin Kang, PhD, and Skip Garner, PhD, serve as investigators. Robin Varghese, PhD • VCOM REAP: Chelation therapy salvages the DNA damaging effects of lead and cadmium on endothelial cells. A clinician from Virginia Circulation Research Center serves as Co- PI on this project. Skip Garner, A prognostic marker and a potential therapeutic target for glioblastoma. Ramu Anandakrishnan, PhD, serves as Co-PI and a faculty member from VTC School of Medicine serves as investigator. Steven Warrington, MD • VCOM REAP: Increased detection of pre-malignant and malignant skin lesions in vulnerable populations. Dr. Warrington is Co-PI on this project with a clinician from Orange Park Medical Center. PhD, is an investigator. • VCOM REAP: OR2T7:

Ramu Anandakrishnan, PhD • VCOM REAP: OR2T7: A prognostic marker and a potential therapeutic target for glioblastoma. Robin Varghese, PhD, serves as Co-PI and a faculty member from VTC School of Medicine serves as investigator. P. Gunnar Brolinson, DO • VCOM REAP (matching funds from VT ICTAS): Development of an image-guided focused ultrasound system for the non- invasive treatment of injured tendons. A collaborator from VT Biomedical Engineering and Mechanics serves as Co-PI along with Dr. Brolinson. Brad McCrady, DO, and a faculty member from VT Biomedical Engineering and Mechanics serve as investigators. This is a two-year project and will continue into 2021. • VCOM REAP (matching funds from VT ICTAS): Mechanisms of mild traumatic brain injury in snow sports. Dr. Brolinson is Co-PI on this project with a collaborator from VT Biomedical Engineering and Mechanics. This is a two-year project and will continue into 2021. Blaise Costa, MPharm, PhD • VCOM & VMCVM One Health Program: Mechanisms and neuroprotective effects of triheteromeric NMDA receptor modulators. A collaborator from VMCVM serves as Co-PI with Dr. Costa on this project. Terry Hrubec, DVM, PhD • VCOM & VMCVM One Health Program: Epitranscriptome dynamics upon neuronal activation: Novel clues for Autism pathology and

Katherine Jamison, PharmD • VCOM REAP: Prevalence of

methicillin resistant Staph aureus over time in resident physicians. Scott Gutovitz, MD, is the Co-PI on this project. Faculty from Orange Park Medical Center and Memorial

Health University Medical Center are investigators.

Al Kozar, DO • VCOM REAP: The effects of light on platelet activity. Beverly Rzigalinski, PhD, is the Co-PI on this study. Pawel Michalak, PhD • VCOM & VMCVM One Health Program: Genomic characterization of the invasive Longhorned tick and its microbiota including the known pathogen, Theileria orientalis. Dr. Michalak is Co-PI on this project with a collaborator from VMCVM. • VCOM REAP: IGPOHOM: An integrative genomics platform for one health and osteopathic medicine. Lin Kang, PhD, serves as an investigator on this project. • VCOM REAP: Third-generation DNA sequencing approaches to rapid characterization of drinking water contamination in El Salvador, Honduras, and the Dominican Republic. Dean Sutphin, PhD, serves as Co-PI. Lin Kang, PhD, and Skip Garner, PhD, serve as investigators.

Chris Reilly, PhD • VCOM & VMCVM One

Health Program: Microbiotic regulation of lupus nephritis.

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