VCOM 2018 Annual Report

Scholarly Activities 2017-2018 T he following list of publications, abstracts, seminars and presentations shows the breadth of research being done at VCOM by faculty, staff and students, as well as the exciting growth of research programs ongoing on each campus.

Faculty Publications

Bradley JH , Harrison A, Corey A, Gentry N, Gregg RK . Ebola virus secreted glycoprotein decreases the anti-viral immunity of macrophages in early inflammatory responses. Cell Immunol. 2018 Feb;324:24-32. PMID: 29195741. Bradley JH , *Stein R, *Randolph B, Arnold J, Gregg RK . T cell resistance to activation by dendritic cells requires long-term culture in simulated microgravity. Life Sciences in Space Research. 2017 Nov;15:55-61. PMID: 29198314. Caldwell M, Hathcock T, Brock KV . Passive protection against anthrax in mice with plasma derived from horses hyper-immunized against Bacillus anthracis Sterne strain. PeerJ. 2017 Dec 15;5:e3907. PMID: 29259839. Caldwell JD , *Londe K, Ochs SD , Hajdu Z , Rodewald A, Gebhart VM, Jirikowski GF: Three steroid-binding globulins, their localization in the brain and nose, and what they might be doing there. Steroids. 2017 Dec 12. Epub ahead of print. PMID: 29246492. Campolettano ET, Brolinson PG , Rowson S. Postural control and head impact exposure in youth football players: Comparison of the balance error scoring system and a force plate protocol. J Appl Biomech. 2017 Nov 1:1-25. PMID: 29091524. Cohen AS, Khalil FK, Welsh EA, Schabath MB, Enkemann SA , Clark ND, Davis A, Zhou J-M, Kim J, Boulware DC, Chen D-T, Haura EB, Morse DL. Cell-surface marker discovery for lung cancer. Oncotarget. In Press. Colquhoun RJ, Magrini MA, Haun CT, Muddle TWD, Tomko PM, Luera MJ, Mackey CS, Vann CG, Martin JS , Young KC , DeFreitas JM, Roberts MD, Jenkins NDM. Muscle phenotype is related to motor unit behavior of the vastus lateralis

during maximal isometric contractions. Physiol Rep. 2018 Mar;6(5). doi: 10.14814/phy2.13636. PMID: 29527830. Dalbo V, Hiskens M, Teramoto M, Kingsley M, Young K , Scanlan A. Residents of Central Queensland, Australia are aware of healthy eating practices but consume unhealthy diets. Sports. 2017;5: 94. doi:10.3390/ sports5040094. Dalbo VJ, Roberts MD, Mobley CB, Ballmann C, Kephart WC, Fox CD, Santucci VA, Conover CF, Beggs LA, Balaez A, Hoerr FJ, Yarrow JF, Borst SE, Beck DT . Testosterone and trenbolone enanthate increase mature myostatin protein expression despite increasing skeletal muscle hypertrophy and satellite cell number in rodent muscle. Andrologia. 2017 Apr; 49(3). doi: 10.1111/and.12622 . PMID: 27246614. Davis, Yang M, Schell MJ, Pledger WJ , Yeatman TJ. PTPRS regulates colorectal cancer RAS pathway activity by inactivating ERK and preventing its nuclear translocation. Scientific Reports. In press. Detweiler MB , Chudhary AS, Murphy PF. Screening for schizophrenia in recruits, active duty soldiers and veterans: Can we do a better Job? Neuropsychiatry. 2017; 7(5):576–85. Detweiler MB , Sherigar RM, Bader G, Kenneth A, Sullivan K, Lutgens B, Kalafat N, Reddy P, Detweiler JD. Association of white matter lesions, cerebral atrophy, intracranial extravascular calcifications, and ventricular-communicating hydrocephalus with delirium among veterans. Southern Medical Journal 2017 Jun; 110(6):432-39. PMID: 28575905.

Anandakrishnan R , Zuckerman DM. Biophysical comparison of ATP-driven proton pumping mechanisms suggests a kinetic advantage for the rotary process depending on coupling ratio. PLoS One. 2017 Mar 20;12(3):e0173500. PMID: 28319179. Beckwith JG, Zhao W, Ji S, Ajamil AG, Bolander RP, Chu JJ, McAllister TW, Crisco JJ, Duma SM, Rowson S, Broglio SP, Guskiewicz KM, Mihalik JP, Anderson S, Schnebel B, Brolinson PG , Collins MW, Greenwald RM. Estimated brain tissue response following impacts associated with and without diagnosed concussion. Ann Biomed Eng. 2018 Feb 22. doi: 10.1007/s10439-018-1999-5 [Epub ahead of print]. PMID: 29470745. Barman R, Kumar S, Pagadala B, Detweiler MB . Cocaine abuse, traumatic brain injury, and preexisting brain lesions as risk factors for Bupropion-associated psychosis. J Clin Psychopharmacol. 2017 Aug;37(4):459-463. PMID: 28590371. Bishop BM, Juba ML, Russo PS, Devine M, Barksdale SM, Scott S, Settlage R, Michalak P , Gupta K, Vliet K, Schnur JM, van Hoek ML. Discovery of novel antimicrobial peptides from Varanus komodoensis (Komodo dragon) by large-scale analyses and de-novo- assisted sequencing using electron- transfer dissociation mass spectrometry. J Proteome Res. 2017 Apr 7;16(4):1470- 1482. PMID: 28164707. Bledsoe D, Tamer C, Mesic I, Madry C, Klein BG, Laube B, Costa BM . Positive modulatory interactions of NMDA receptor GluN1/2B ligand binding domains attenuate antagonists activity. Front Pharmacol. 2017 May 9;8:229. PMID: 28536523

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