VCOM 2017 Annual Report

Carolinas Campus Students involved in Research Biomedical Research VCOM Students Project Title Mentor Name

Ariel Katsimpalis, Class of 2019 Nathan Gentry, Class of 2019 Ashley Corey, Class of 2019 Sara Afridi, Class of 2020 Paige Bell, Class of 2018 Eric Ginsberg, Class of 2018 McKenzie Sorrell, Class of 2017 Ariel Katsimpalis, Class of 2019

Effect of Zaire Ebolavirus soluble viral proteins upon the functions of innate immune cells (VCOM REAP)

Randal Gregg, PhD Jillian Bradley, PhD

Evaluate the effectiveness of the lymphatic pump technique on immunity in a DSS colitis model

Jennifer Berglind, PhD

Effect of Ebola virus secreted glycoprotein, upon natural killer cell cytotoxicity and cytokine secretion Effect of Ebola virus proteins, VP40 and secreted glycoprotein, upon macrophage differentiation, polarization, and function The effect of Ebola virus proteins, VP40 and sGP, on dendritic cells cytokine production, antigen presentation, and T-cell activation The effect of Ebola virus proteins on T helper cell cytokine production Determining the mechanism behind the modulatory effects of sGP on macrophage and dendritic cell functions Determining the mechanism behind the modulatory effects of sGP on macrophage and dendritic cell functions

Jillian Bradley, PhD

Ashley Corey, Class of 2019

Jillian Bradley, PhD

Nathan Henry, Class of 2020

Jillian Bradley, PhD

Michael Todd, Class of 2020

Jillian Bradley, PhD

Nathan Gentry, Class of 2019

Jillian Bradley, PhD

Lindsey Shapiro, Class of 2020 Clara Hitchcock, Class of 2020 Dakota Kulis, Class of 2020 Lauren Needell, Class of 2020 Arnav Vasudeva, Class of 2018 Sara LaChance, DO, Class of 2016 Eric Bradley, Class of 2019 Adina Gaughran, Class of 2019 Minerva Andre, Class of 2019 Stephanie Minter, Class of 2017 Brian DiGiacinto, Class of 2017 Grant Bludorn, Class of 2018 Jordan Lakin, Class of 2018 William Boos III, Class of 2018 Jason Schreiber, Class of 2019

Jillian Bradley, PhD

Making intestinal organoids from induced pluripotent stem cells Fc chimera cancer vaccine for the prevention and immunotherapy of cancer

Stephan Brown, PhD, MD

Randal Gregg, PhD Jennifer Arnold

Antigen presentation and immune cell viability in simulated microgravity Effects of simulated microgravity upon human pancreatic cancer cell growth and resistance to natural killer cell cytotoxicity

Randal Gregg, PhD Jennifer Arnold Randal Gregg, PhD Jennifer Arnold

Brianna Goley, Class of 2018 Elizabeth Ullrich, Class of 2018

Impact of simulated microgravity upon tumor development in vivo

Randal Gregg, PhD Jennifer Arnold

Emily Molina, Class of 2018

Natural killer cell and T cell function in simulated microgravity Randal Gregg, PhD Jennifer Arnold

Leandra Jelinek, Class of 2017 Micah Thomas, Class of 2018

Variations of human vasculature

David Jaynes, PhD

Neelam Patel, Class of 2018

CRISPR engineered cardiomyocytes to model Danon disease, a lysosomal cardiomyopathy Patient derived human induced stem cell (iPSC) models of Gaucher Type 2, a neurodevelopmental disease

Cindy E. McKinney, PhD

Jennifer Uspal, Class of 2017 Megan Corrigan-Cummins, Class of 2017 Duy-Tan Ngo, Class of 2019

Cindy E. McKinney, PhD

Lauren Little, DO, Class of 2016

Investigating calcium mobilization in estradiol stimulated NGF differentiated PC-12 cells and the interaction between intracel- lular SHBG and cytoplasmic estradiol receptors (ER α and ER β )

Scott Ochs, PhD Jack Caldwell, PharmD

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