VCOM 2017 Annual Report

Extramurally Funded Research (continued)

Jim Palmieri, PhD Dr. Palmieri is an associate professor for microbiology and immunology at VCOM–Virginia. He is currently a co-principal investigator on a collaborative project funded by the Virginia Biosciences Health Research Corporation (VBHRC): • VBHRC: Nanotrap tick-panel test development ; in collaboration with Virginia Tech, Ceres Nanosciences, and George Mason University. Dr. Palmieri and his group are working to develop a novel Nanotrap urine-based test for Lyme disease. Chris Reilly, PhD Dr. Reilly is the discipline chair for cell biology and physiology at VCOM–Virginia. He has an active research program with a focus on lupus nephritis and HDAC inhibition. Through his lab at Virginia Tech, he has extensive funding from both federal agencies and industry: • National Institutes of Health: MicroRNA expression in the NZB/W lupus mouse (R15). • National Institutes of Health: Prolonged inhibition of pathologic neovascularization by catalytic antioxidants (R01). • Acetylon Pharmaceuticals: Inhibition of SLE with the HDAC-6 Inhibitor ACY-1083 in NZB/W female mice .

available to reduce stroke induced mortality and morbidity. Dr. Costa also has an active research program focused on cranial osteopathic manipulation (COM); specifically, how COM may clear metabolic wastes using an animal model of Alzheimer’s disease. Harold “Skip” Garner, PhD Dr. Garner is the executive director of the Primary Care Research Network and the Center for Bioinformatics and Genetics at VCOM. His main research focuses are the development and application of bioinformatics resources, and translation, applications research, and training of clinicians in personalized medicine and ethics. He has several funded projects ongoing: • Via-Bradley College of Engineering Foundation:

Via Bioinformatics and Clinical Genetics Network . This grant of $1.2 million funds his team’s research into the genetic basis of disease, which will impact primary and specialized care.

• Children’s Research Institute: Biomarkers for meduloblastoma. • Carilion Clinic: Genetic markers for responders to dofetilide therapy in persistent atrial fibrillation . • National Science Foundation: Determining feasibility and scalability of a life/medical science hybrid-core based platform . Dr. Brolinson is the co-principle investigator on this project.

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