VCOM 2016 Annual Report

“ Research projects help me feel like I am directly contributing to the progress of medicine. It allowed me to grasp concepts in a more tangible way. Research is really a two-way street, you get out of it what you contribute... I want to impact medicine through my contributions to research. ” - Jordan Lakin Class of 2018, VCOM–Carolinas Faculty Publications (continued)

on golf performance and fatigue during a competitive tournament. Medicine and Science in Sport and Exercise. 2016 Jan;48(1):132- 8. PMID: 26285020. Newton AL , Hanks LJ, Judd S, Wallace S, Durant N, Casazza K. Low HDL cholesterol may lead to disruption of bone remodeling in obese early pubertal girls. International Journal of Orthopaedics 2015;2(3):312-6. Palomares RA, Brock KV , Walz PH. Differential expression of pro-inflammatory and anti-

autoimmunity. Proc Natl Acad Sci USA. 2015 Aug 25;112(34):10774-9. PMID: 26261340.

Regna NL, Chafin CB, Hammond SE, Puthiyaveetil AG, Caudell, DL, Reilly CM . Class I and II histone deacetylase inhibition by ITF2357 reduces SLE pathogenesis In vivo. Clinical Immunology. 2014 Mar; 151(1):29-42. PMID: 24503172. Regna NL, Reilly CM . Isoform-selective HDAC inhibition in autoimmune disease. Journal of Clinical & Cellular Immunology. 2014 April; 5:207. doi: 10.4172/2155-9899.1000207. Regna NL, Vieson MD, Gojmerac AM, Luo XM, Caudell DL, Reilly CM . HDAC expression and activity is upregulated in diseased lupus-prone mice. Int Immunopharmacol. 2015 Dec;29(2):494- 503. PMID: 26471208. Regna NL, Vieson MD, Luo XM, Chafin CB, Puthiyaveetil AG, Hammond SE, Caudell DL, Jarpe MB, Reilly CM . Specific HDAC6 inhibition by ACY-738 reduces SLE pathogenesis in NZB/W mice. Clin Immunol. 2016 Jan;162:58-73. PMID:26604012. Roberts M, Holland A, Kephart W, Mumford P, Mobley C, Lowery R, Fox C, McCloskey A, Shake J, Mesquita P, Patel R, Martin J, Young K , Kavazis A, Wilson J. A low-carbohydrate diet does not impair the acute and chronic hypertrophic responses to resistance exercise in rodents. Submitted to Journal of Applied Physiology. In Press. Robinson TB , Register AI, Ebner C, Orr K. Reducing Early Discontinuation Rates of Subdermal Contraception in Your Clinical Practice. Osteopathic Family Physician. 2015 Mar/ Apr;7(2):24-8. Rowson S, Duma SM, Greenwald RM, Beckwith JG, Chu JJ, Guskiewicz KM, Mihalik JP, Crisco JJ, Wilcox BJ, McAllister TW, Maerlender AC, Broglio SP, Schnebel B, Anderson S, Brolinson PG . Can helmet design reduce the risk of concussion in football? Journal of Neurosurgery. 2014 Apr; 120(4):919-22. PMID: 24484225. Scheel TK, Kapoor A, Nishiuchi E, Brock KV , Yu Y, Andrus L, Gu M, Renshaw RW, Dubovi EJ, McDonough SP, Van de Walle GR, Lipkin WI, Divers TJ, Tennant BC, Rice CM. Characterization of nonprimate hepacivirus and construction of a functional molecular clone. Proc Natl Acad Sci USA. 2015 Feb 17; 112(7):2192-7. PMID: 25646476. Shah AV, Mullens DJ, Van Duyn LJ, Januchowski RP . Multitasking behaviors of osteopathic medical students. J Am Osteopath Assoc. 2014 Aug; 114(8):654-9. PMID: 25082973. Sharma S, Ma L, Pledger WJ . p27kip inhibits the cell cycle through non-canonical G1/S phase specific gate keeper mechanism. Cell Cycle. 2015 Dec 17;14(24):3954-64. PMID: 26697844.

inflammatory cytokines during experimental infection with low or high virulence bovine viral diarrhea virus in beef calves. Vet Immunol Immunopathol. 2014 Feb 15; 157)3- 4):149-54. PMID: 24461321. Palomares RA, Hurley DJ, Woolums AR, Parrish JE, Brock KV . Analysis of mRNA expression for genes associated with regulatory T lymphocytes (CD25, FoxP3, CTLA4, and IDO) after experimental infection with bovine viral diarrhea virus of low or high virulence in beef calves. Comp Immunol Microbiol Infect Dis. 2014 Dec; 37(5-6): 331-8. PMID: 25456194. Palomares RA, Parrish JE, Woolums AR, Brock KV , Hurley DJ. Expression of toll-like receptors and co-stimulatory molecules in lymphoid tissue during experimental infection of beef calves with bovine viral diarrhea virus of low and high virulence. Vet Res Commun. 2014 Dec; 38(4):329- 35. PMID: 25145871. Palomares RA, Sakamoto K, Walz HL, Brock KV , Hurley DJ. Acute infection with bovine viral diarrhea virus of low or high virulence leads to depletion and redistribution of WC1(+) γδ T cells in lymphoid tissues of beef calves. Vet Immunol Immunopathol. 2015 Oct 15;167(3-4):190-5. PMID: 26282369. Parson C, Smith V, Krauss C, Banerjee HN, Reilly C , Krause JA, Wachira JM, Giri D, Winstead A, Mandal SK. Anticancer Properties of Novel Rhenium Pentylcarbanato Compounds against MDA-MB-468(HTB-132) Triple Node Negative Human Breast Cancer Cell Lines. Br J Pharm Res. 2015 Feb 1;4(3):362-367. PMID:25419517. Prisby RD, Alwood JS, Behnke BJ, Stabley JN, McCullough DJ , Ghosh P, Globus RK, Delp MD. Effects of hindlimb unloading and ionizing radiation on skeletal muscle resistance artery vasodilation and its relation to cancellous bone in mice. J Appl Physiol (1985). 2016 Jan 15;120(2):97-106. doi: PMID: 26472865. Ravishankar B, Liu H, Shinde R, Chaudhary K, Xiao W, Bradley J , Koritzinsky M, Madaio M, McGaha TL. The amino acid sensor GCN2 inhibits inflammatory responses to apoptotic cells promoting tolerance and suppressing systemic

Melin VE, Johnstone DW, Etzkorn FA, Hrubec TC . Drinking water treatment is not associated with an observed increase in neural tube defects in mice. Environmental Monitoring and Assessment. 2014 Jun; 186(6):3717-24. PMID: 24497082. Melin VE, Potineni H, Hunt P, Griswold J, Siems B, Were SR, Hrubec TC . Exposure to common quaternary ammonium disinfectants decreases fertility in mice. Reproductive Toxicology. 2014 Dec; 50:163-70. PMID: 25483128. Melin VE, Shanteau P, Melin TE, Dessify B, Nguyen C, Shea CS, Hrubec TC . Quaternary ammonium disinfectants cause subfertility in mice by targeting both male and female reproductive processes. Reproductive Toxicology. 2016 Jan;59:159-66. PMID: 26582257. Michalak K, Maciak S, Kim YB, Santopietro G, Oh JH, Kang L, Garner HR , Michalak P. Nucleolar dominance and maternal control of 455 rDNA expression. Proc Biol Sci. 2015 Dec 7;282(1820):20152201. PMID: 26645200. Mobley C, Fox C, Thompson M, Healy J, Santucci V, Kephart W, McCloskey A, Kim M, Pascoe D, Martin J, Moon J, Young K , Roberts M. Comparative effects of whey protein versus L-leucine on skeletal muscle protein synthesis and markers of ribosome biogenesis following Mobley CB, Kephart WC, Fox CD, Conover CF, Beggs LA, Otzel DM, Balaez A, Yarrow JF, Borst SE, Beck DT , Roberts MD. Effects of testosterone on markers of skeletal muscle ribosome biogenesis. Andrologia. 2016 Jan 19. PMID:26781353. Mount MG, White NR, Nguyen CL, Orr RK , Hird RB. Evaluating one day versus two days preoperative lymphoscintigraphy protocols for sentinel lymph node biopsy in breast cancer. Am Surg. 2015 May;81(5):454-7. PMID: 25975327. Mumford P, Tribby A, Hollaway K, Poole C, Roberts M, Scanlan A, Dalbo V, Moon J, Young K . Effects of a caffeine-containing supplement resistance exercise. Amino Acids. 2016 Mar;48(3):733-50. PMID: 26507545.

Sharma S, Pledger WJ . The non-canonical

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