VCOM 2016 Annual Report

Carolinas Campus Research

Biomedical Research Faculty Name

Project Title

VCOM Students

Jennifer Berglind, PhD Jennifer Berglind, PhD

Effect of a gluten-free diet on immunity in a DSS colitis model Evaluate the effectiveness of the lymphatic pump technique on immunity in a DSS colitis model The contribution of NLR proteins in modulating gastrointestinal inflammation following exposure to wheat gluten

Paige Bell, Eric Ginsberg, Erin Iverson, McKenzie Sorrell

Jennifer Berglind, PhD

Jillian Bradley, PhD The effect of microgravity on macrophage differentiation and polarization Stephan Brown, PhD, MD Making intestinal organoids from induced pluripotent stem cells Stephan Brown, PhD, MD Role of LGR5 signaling in skeletal muscle myoblast cells (skMDC) Randal Gregg, PhD Jennifer Arnold Fc chimera cancer vaccine for the prevention and immunotherapy of cancer

Arnav Vasudeva

Sara LaChance, Eric Bradley, Adina Gaughran, Minerva Andre

Randal Gregg, PhD Jillian Bradley, PhD Jennifer Arnold Randal Gregg, PhD Jillian Bradley, PhD Jennifer Arnold Randal Gregg, PhD Jillian Bradley, PhD Jennifer Arnold Randal Gregg, PhD Jillian Bradley, PhD Jennifer Arnold Randal Gregg, PhD Jillian Bradley, PhD Jennifer Arnold Randal Gregg, PhD Jillian Bradley, PhD Jennifer Arnold David Jaynes, PhD

Antigen presentation and immune cell viability in simulated microgravity

Stephanie Minter, Brian DiGiacinto

Effect of Ebola virus proteins, secreted glycoprotein and viral protein 40, upon natural killer cell function

Effect of Ebola virus secreted glycoprotein upon macrophage polarization and function

Effects of simulated microgravity upon human pancreatic cancer cell growth and resistance to natural killer cell cytotoxicity

Grant Bludorn, Jordan Lakin, William Boos III, Jason Schreiber

Impact of simulated microgravity upon tumor development in vivo Brianna Goley, Elizabeth Ullrich

Natural killer cell and T cell function in simulated microgravity

Emily Molina

Variations of human vasculature

Leandra Jelinek, Micah Thomas

Cindy E. McKinney, PhD

Assessing the effectiveness of clinical case studies supplementing Block 1 genetics lectures CRISPR engineered cardiomyocytes to model Danon disease, a lysosomal cardiomyopathy IPSC cells from human blood to model X-linked intellectual disability: A collaboration with Greenwood Genetics Patient derived human induced stem cell (iPSC) models of Gaucher Type 2, a neurodevelopmental disease

Cindy E. McKinney, PhD

Neelam Patel

Cindy E. McKinney, PhD

Cindy E. McKinney, PhD

Jennifer Uspal, Megan Corrigan-Cummins, Duy-Tan Ngo

Scott Ochs, PhD

Exploring the cellular mechanisms of toxicity of noradrenochrome and adrenochrome on endothelial cells

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