VCOM 2016 Annual Report

Current Research

Virginia Campus Biomedical Research Faculty Name

Project Title

VCOM Students

Blaise Costa, PhD

Elucidating the molecular mechanisms of cranial osteopathic manipulation Identifying molecular determinants of novel drug target in NMDA receptors The role of tri-heteromeric (GluN1/2/3) NMDA receptors in stroke and its mitigation Nanoparticles to deliver antisense nucleic acid constructs as therapeutics for intracellular bacterial infections Are quat disinfectants developmental or reproductive toxins? NMDA receptor subunit specific drug discovery

Blaise Costa, PhD

Lucas Kane

Blaise Costa, PhD Blaise Costa, PhD

Shaadi Elswaifi, PhD Renee Prater, PhD, DVM Terry Hrubec, DVM, PhD

Brian Dessify, Christina Nguyen, Rosemarie DiPeppi, Hiral Patel, Reza Razvi, Caroline Shea

Terry Hrubec, DVM, PhD Terry Hrubec, DVM, PhD

Developmental immunotoxicity of quat disinfectants

Identification of transgenerational methylome changes from disinfectant

Caroline Shea

Terry Hrubec, DVM, PhD

Screening tap water for development and reproductive toxicants Tyler Chapman, Claire Repine, Craig Garafola

Teresa Johnson, PhD Teresa Johnson, PhD Teresa Johnson, PhD Teresa Johnson, PhD Renee Prater, PhD, DVM Teresa Johnson, PhD Renee Prater, PhD, DVM Teresa Johnson, PhD Susan Meacham, PhD Chevon Thorpe, PhD

Development of a nosocomial bacterial vaccine

Kyle Walding, Bruce Gutierrez

Evaluation of respiratory syncytial virus pathogenesis

The Role of Indole 2,3-Dioxygenase in Brucella pathogenesis

Development of a point-of-care diagnostic kit for bacterial and viral pneumonia

Kyle Walding, Bruce Gutierrez, Asish Gulati Kyle Walding, Bruce Gutierrez, Asish Gulati Kyle Walding, Bruce Gutierrez

Establishment of the lamb model of respiratory syncytial virus

Effect of boron on UV-induced skin cancer

James Mahaney, PhD

Molecular mechanism of calcium transport in the heart

Greg Rodden

Chris Reilly, PhD Chris Reilly, PhD Chris Reilly, PhD

HDAC6 inhibition in SLE

MicroRNA expression in the NZB/W lupus mouse (NIH)

Prolonged inhibition of pathologic neovascularization by catalytic antioxidants

Chris Reilly, PhD

Selective inhibition of HDAC6 in SLE

Beverly Rzigalinski, PhD Beverly Rzigalinski, PhD

Biochemical effects of OMM at the cellular level

Cerium-containing nanoparticles for amelioration of neurodegenerative conditions

Beverly Rzigalinski, PhD

Cerium Oxide nanoparticles in the treatment of traumatic brain injury Function, evaluation and applications of mosquito specific smRNAs

Chevon Thorpe, PhD

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