Carolinas Research Day 2021

Clinical Case-Based Studies

03 Respiratory Syncytial Virus (RSV) Associated with Syndrome of Inappropriate Antidiuretic Hormone (SIADH) in Pediatric Patients A Case Report

Megan Donaldson, OMS-III, Katelyn Hernandez, OMS-III, Hanna S. Sahhar, MD, FAAP, FACOP

Edward Via College of Osteopathic Medicine-Carolinas, Pediatric Intensive Care Unit (PICU) at Spartanburg Regional Medical Center

Abstract: Respiratory syncytial virus is a known cause of bronchiolitis or pneumonia in infants. Although rare, in documented cases of RSV, children can develop euvolemic hyponatremia, more commonly seen in those in the intensive care setting. These cases show similar symptomatology, but vary in the timing of significant hyponatremic symptoms. Respiratory syncytial virus was confirmed in both individuals by the FilmArray respiratory panel. The children were then diagnosed with hyponatremia, however there is currently no evidence to link this hyponatremia to elevated levels of antidiuretic hormone. These cases emphasize the need to consider metabolic and endocrine derangements in the diagnosis of critical RSV related respiratory infections to ensure proper treatment and prevention of worse clinical outcomes

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